Therapeutic Potential of Perineural Invasion, Hypoxia and Desmoplasia in Pancreatic Cancer
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چکیده
منابع مشابه
Association of diabetes and perineural invasion in pancreatic cancer
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PURPOSE We investigated the contribution of Sonic hedgehog (SHH) to pancreatic cancer progression. EXPERIMENTAL DESIGN We expressed SHH in a transformed primary ductal-derived epithelial cell line from the human pancreas, transformed hTert-HPNE (T-HPNE), and evaluated the effects on tumor growth. We also directly inhibited the activity of SHH in vivo by administering a blocking antibody to mi...
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ژورنال
عنوان ژورنال: Current Pharmaceutical Design
سال: 2012
ISSN: 1381-6128
DOI: 10.2174/13816128112092395